发明授权
- 专利标题： Arylthiazolidinedione and aryloxazolidinedione derivatives
- 专利标题（中）： 芳基噻唑烷二酮和芳基恶唑烷二酮衍生物
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申请号： US09595802申请日： 2000-06-16
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公开(公告)号： US06399640B1公开(公告)日： 2002-06-04
- 发明人: Soumya P. Sahoo , Conrad Santini , Julia K. Boueres , James V. Heck , Edward Metzger , Victoria K. Lombardo
- 申请人： Soumya P. Sahoo , Conrad Santini , Julia K. Boueres , James V. Heck , Edward Metzger , Victoria K. Lombardo
- 主分类号： A61K31421
- IPC分类号： A61K31421
摘要：
Substituted 5-aryl-2,4-thiazolidinediones or 5-aryl-2,4-oxazolidinediones that also carry a second substituent in the 5-position of the heterocyclic ring are potent agonists of PPAR, and are therefore useful in the treatment, control or prevention of diabetes, hyperglycemia, hyperlipidemia (including hypercholesterolemia and hypertriglyceridemia), atherosclerosis, obesity, vascular restenosis, and other PPAR &agr;, &dgr; and/or &ggr; mediated diseases, disorders and conditions.