发明授权
- 专利标题： Methods for producing chiral aldehydes
- 专利标题（中）： 生产手性醛的方法
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申请号： US09831925申请日： 2001-05-15
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公开(公告)号： US06399834B1公开(公告)日： 2002-06-04
- 发明人: Walter Leitner , Sabine Kainz , Daniel Koch , Giancarlo Francio
- 申请人： Walter Leitner , Sabine Kainz , Daniel Koch , Giancarlo Francio
- 优先权： DE19853748 19981121
- 主分类号： C07C4550
- IPC分类号： C07C4550
摘要：
The present invention relates to methods for producing chiral aldehydes by the enantioselective hydroformylation of prochiral substrates with the aid of a catalyst consisting of a transition metal and a chiral ligand, characterized in that said chiral ligand is a compound of general formula 1 wherein the rings R7-R10 drawn with dotted lines are optional and one or more of rings R1-R6 or R7-R10 are substituted with one or more independently selected substituents of general formula —(CH2)x(CF2)yF(x=0-5; y=1-12) or their branched isomers. In particular, the invention relates to the conducting of the mentioned methods in compressed (liquid or supercritical) carbon dioxide as the reaction medium.