发明授权
- 专利标题： HIV integrase inhibitors
- 专利标题（中）： HIV整合酶抑制剂
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申请号： US09355692申请日： 1999-10-25
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公开(公告)号： US06403347B1公开(公告)日： 2002-06-11
- 发明人: Gerald F. Bills , Russell B. Lingham , Ali Shafiee , Keith C. Silverman , Sheo Bux Singh , Deborah L. Zink , Fernando Pelaez , Ana M. Teran
- 申请人： Gerald F. Bills , Russell B. Lingham , Ali Shafiee , Keith C. Silverman , Sheo Bux Singh , Deborah L. Zink , Fernando Pelaez , Ana M. Teran
- 主分类号： A61K3135
- IPC分类号： A61K3135
摘要：
Natural products such as certain chaetochromins are described. These compounds are useful in the inhibition of HIV integrase, the prevention or treatment of infection by HIV and the treatment of AIDS, either as compounds, pharmaceutically acceptable salts, pharmaceutical composition ingredients, whether or not in combination with other antivirals, immunomodulators, antibiotics or vaccines. Methods of treating AIDS and methods of preventing or treating infection by HIV are also described.