发明授权
US06410535B1 Prophylactic or therapeutic agents for diseases having vascular dysfunction associated with insulin resistance
有权
具有与胰岛素抵抗相关的血管功能障碍的疾病的预防或治疗剂
- 专利标题： Prophylactic or therapeutic agents for diseases having vascular dysfunction associated with insulin resistance
- 专利标题（中）： 具有与胰岛素抵抗相关的血管功能障碍的疾病的预防或治疗剂
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申请号： US09427579申请日： 1999-10-27
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公开(公告)号： US06410535B1公开(公告)日： 2002-06-25
- 发明人: Atsunori Kashiwagi , Kazuya Shinozaki , Yoshihiko Nishio , Tomio Okamura , Noboru Toda , Ryuichi Kikkawa
- 申请人： Atsunori Kashiwagi , Kazuya Shinozaki , Yoshihiko Nishio , Tomio Okamura , Noboru Toda , Ryuichi Kikkawa
- 优先权： JP10-047720 19980227
- 主分类号： A61K31495
- IPC分类号： A61K31495
摘要：
It is an object of the present invention to provide a pharmaceutical composition for effectively preventing or improving diseases having vascular dysfunction associated with insulin resistance. The present invention provides pharmaceutical compositions for preventing or treating diseases having vascular dysfunction associated with insulin resistance, comprising as an active ingredient a compound of the formula (I): wherein R1 and R2 each represents a hydrogen atom or taken together with each other represent a single bond, while R3 represents —CH(OH)CH(OH)CH3, —CH(OCOCH3)CH(OCOCH3)CH3, —CH3, —CH2OH or a phenyl group when R1 and R2 each represents a hydrogen atom, or —COCH(OH)CH3 when R1 and R2 together represents a single bond, or a pharmaceutically acceptable salt thereof.
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