发明授权
US06420341B1 Sulphur derivatives with a retroamide bond as endothelin-converting enzyme inhibitors
失效
具有逆转肽键的硫衍生物作为内皮素转化酶抑制剂
- 专利标题： Sulphur derivatives with a retroamide bond as endothelin-converting enzyme inhibitors
- 专利标题（中）： 具有逆转肽键的硫衍生物作为内皮素转化酶抑制剂
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申请号： US09142288申请日： 1998-10-30
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公开(公告)号： US06420341B1公开(公告)日： 2002-07-16
- 发明人: Pierre Deprez , Jacques Dumas , Jacques Guillaume
- 申请人： Pierre Deprez , Jacques Dumas , Jacques Guillaume
- 优先权： FR9602674 19960304
- 主分类号： A61K3800
- IPC分类号： A61K3800
摘要：
Products of formula (1), wherein R1 is particularly phonyl or biphenyl optionally substituted by halogen n1 and n2 are 0 or 1, R2 is particularly hydrogen or methyl substituted by phenyl, which may in turn be substituted, and A is partcularly carboxy or alkyl substituted particularly by phenoxy, as well as all isomers and organic and inorganic base addition salts therof, are disclosed.
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