发明授权
- 专利标题： Inhibitors of IMPDH enzyme
- 专利标题（中）： IMPDH酶抑制剂
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申请号： US09428609申请日： 1999-10-27
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公开(公告)号： US06420403B1公开(公告)日： 2002-07-16
- 发明人: Edwin J. Iwanowicz , T. G. Murali Dhar , Katerina Leftheris , Chunjian Liu , Toomas Mitt , Scott H. Watterson , Joel C. Barrish
- 申请人： Edwin J. Iwanowicz , T. G. Murali Dhar , Katerina Leftheris , Chunjian Liu , Toomas Mitt , Scott H. Watterson , Joel C. Barrish
- 主分类号： C07D26334
- IPC分类号： C07D26334
摘要：
The present invention discloses the identification of the novel inhibitors of IMPDH (inosine-5′-monophosphate dehydrogenase). The compounds and pharmaceutical compositions disclosed herein are useful in treating or preventing IMPDH-associated disorders, such as transplant rejection and autoimmune diseases.
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