发明授权
US06441144B1 Method for repairing dual virally inactivated immune globulin for intravenous administration
失效
用于修复用于静脉内施用的双重病毒灭活的免疫球蛋白的方法
- 专利标题: Method for repairing dual virally inactivated immune globulin for intravenous administration
- 专利标题(中): 用于修复用于静脉内施用的双重病毒灭活的免疫球蛋白的方法
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申请号: US09316117申请日: 1999-05-20
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公开(公告)号: US06441144B1公开(公告)日: 2002-08-27
- 发明人: Raja R. Mamidi , Andranik Bagdasarian , Gorgonio Canaveral , Kazuo Takechi
- 申请人: Raja R. Mamidi , Andranik Bagdasarian , Gorgonio Canaveral , Kazuo Takechi
- 主分类号: C07K1606
- IPC分类号: C07K1606
摘要:
A process for producing an intravenously-administrable gamma globulin solution substantially free of contaminating viruses by fractionating an impure gamma globulin solution and then treating the purified gamma globulin, with a solvent-detergent for viral inactivation and a heat treating for viral inactivation. Thereafter, denatured impurities, residual solvent and aggregate generated by the heat treatment are removed from the gamma globulin.
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