发明授权
- 专利标题： Recombinant and mutant adenoviruses
- 专利标题（中）： 重组和突变型腺病毒
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申请号： US09545481申请日： 2000-04-07
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公开(公告)号： US06451319B1公开(公告)日： 2002-09-17
- 发明人: Christina H. Chiang , Mark D. Cochran
- 申请人： Christina H. Chiang , Mark D. Cochran
- 主分类号： A61K3912
- IPC分类号： A61K3912
摘要：
The present invention provides novel viral vectors. In one embodiment, the present invention provides mutant and recombinant bovine adenoviruses having a deletion and/or insertion of DNA in the early gene region 4 (E4). In another embodiment, the present invention provides mutant and recombinant bovine adenovirus 1 viruses having a deletion and/or insertion of DNA in the early gene region 3 (E3). The present invention also contemplates the use of the viral vectors for vaccination, gene therapy or other applications as suitable.
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