发明授权
- 专利标题： Multipartite high-affinity nucleic acid probes
- 专利标题（中）： 多部分高亲和力核酸探针
-
申请号： US09610155申请日： 2000-06-30
-
公开(公告)号： US06451588B1公开(公告)日： 2002-09-17
- 发明人: Michael Egholm , Caifu Chen
- 申请人： Michael Egholm , Caifu Chen
- 主分类号： C12M134
- IPC分类号： C12M134
摘要：
The invention provides a collection of probes useful for hybridizing to a target nucleic acid. The probes associate with each other, binding with high affinity to the target nucleic acid, to form three-way junctions and other complexes. At least one of the probes in each collection includes a nucleic acid analog. Methods using the probes in hybridization and as primers are also provided.
信息查询
