An MRI system is provided with normal and quiet modes of operation. The quiet mode may be selected from an operator station, such as via a graphical user interface. When the quiet mode of operation is selected, configuration parameters are used for the particular pulse sequence to be executed in the examination. The configuration parameters for the quiet mode of operation may be derived from those of the normal mode of operation. The quiet mode of operation may, for example, employ gradient pulses having reduced amplitudes and slew rates as compared to those employed in the normal mode of operation. The reduced amplitudes and slew rates, along with changes in timing of the pulses and between pulses of the pulse sequence of the examination result in reduced acoustic noise for accommodating more sensitive patients.