发明授权
- 专利标题: Nucleic acids for identifying anti-fungal agents, and uses related thereto
- 专利标题(中): 用于鉴定抗真菌剂的核酸及其相关用途
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申请号: US08771212申请日: 1996-12-20
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公开(公告)号: US06455281B1公开(公告)日: 2002-09-24
- 发明人: Vivian Berlin , Veronique Damagnez , Susan E. Smith
- 申请人: Vivian Berlin , Veronique Damagnez , Susan E. Smith
- 主分类号: C12N1552
- IPC分类号: C12N1552
摘要:
The present invention relates to rapid, reliable and effective assays for screening and identifying pharmaceutically effective compounds that specifically inhibit the biological activity of fungal GTPase proteins, particularly GTPases involved in cell wall integrity, hyphael formation, and/or other cellular functions critical to pathogenesis. Another aspect of the present invention relates to novel Candida genes and gene products.