发明授权
US06458779B1 Hydroxamic acid derivatives as inhibitors of the production of human CD23 and of the TNF release
失效
羟肟酸衍生物作为人CD23的产生抑制剂和TNF释放
- 专利标题： Hydroxamic acid derivatives as inhibitors of the production of human CD23 and of the TNF release
- 专利标题（中）： 羟肟酸衍生物作为人CD23的产生抑制剂和TNF释放
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申请号： US09701946申请日： 2001-04-05
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公开(公告)号： US06458779B1公开(公告)日： 2002-10-01
- 发明人: Andrew Faller , David Timothy MacPherson , Peter Henry Milner , Jayshree Mistry , John Gerald Ward
- 申请人： Andrew Faller , David Timothy MacPherson , Peter Henry Milner , Jayshree Mistry , John Gerald Ward
- 优先权： GB9813451 19980622
- 主分类号： A61K31545
- IPC分类号： A61K31545
摘要：
Compounds of Formula (1) wherein: R is methyl substituted by one to three groups from alkyl, aryl, alkenyl, and alkynyl; n is ) or 1; R1 is arylmethyl or heterocyclylmethyl; R2 is alkyl, alkenyl, cycloalkyl or cycloalkenyl; and R3 is hydrogen, alkyl, alkenyl, alkynyl or aryl; are useful in the treatment of disorders mediated y s-CD23.
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