发明授权
- 专利标题： 7-hexanoyltaxol and methods for preparing the same
- 专利标题（中）： 7-己酰紫杉醇及其制备方法
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申请号： US09688753申请日： 2000-10-16
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公开(公告)号： US06469050B1公开(公告)日： 2002-10-22
- 发明人: Christopher K. Murray , Qun Y. Zheng , Sagar R. Shakya
- 申请人： Christopher K. Murray , Qun Y. Zheng , Sagar R. Shakya
- 主分类号： A61K31337
- IPC分类号： A61K31337
摘要：
An antitumor compound of formula (5): Also provided by the present invention is a method of preparing a compound of formula (5) whereby diesterification of the alcohol groups located at the 2′and 7 positions of paclitaxel is followed by the hydrolysis of the 2′hexanoate group resulting in 7-hexanoyltaxol.
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