发明授权
- 专利标题： Inhibitors of &agr;4&bgr;1 mediated cell adhesion
- 专利标题（中）： α4β1介导的细胞粘附抑制剂
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申请号： US09102584申请日： 1998-06-23
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公开(公告)号： US06482849B1公开(公告)日： 2002-11-19
- 发明人: Thomas J. Lobl , Bradley R. Teegarden , Alexander Polinsky , Gilbert M. Rishton , Masafumi Yamagishi , Steven Tanis , Jed F. Fisher , Edward W. Thomas , Robert A. Chrusciel
- 申请人： Thomas J. Lobl , Bradley R. Teegarden , Alexander Polinsky , Gilbert M. Rishton , Masafumi Yamagishi , Steven Tanis , Jed F. Fisher , Edward W. Thomas , Robert A. Chrusciel
- 主分类号： A61K3127
- IPC分类号： A61K3127
摘要：
The present invention relates to small molecules according to the formula [I]: which are potent inhibitors of &agr;4&bgr;1 mediated adhesion to either VCAM or CS-1 and which can be used for treating or preventing &agr;4&bgr;1 adhesion mediated conditions in a mammal such as a human.