发明授权
US06489299B2 Methods for treatment of multiple sclerosis using peptide analogues at position 91 of human myelin basic protein
失效
使用肽类似物在人髓磷脂碱性蛋白的第91位治疗多发性硬化症的方法
- 专利标题： Methods for treatment of multiple sclerosis using peptide analogues at position 91 of human myelin basic protein
- 专利标题（中）： 使用肽类似物在人髓磷脂碱性蛋白的第91位治疗多发性硬化症的方法
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申请号： US09989476申请日： 2001-11-19
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公开(公告)号： US06489299B2公开(公告)日： 2002-12-03
- 发明人: Lawrence Steinman , Nicholas Ling , Paul J. Conlon , Amitabh Gaur
- 申请人： Lawrence Steinman , Nicholas Ling , Paul J. Conlon , Amitabh Gaur
- 主分类号： A61K3810
- IPC分类号： A61K3810
摘要：
Peptide analogues of human myelin basic protein containing residues 87-99 are provided. Residue 91 of the peptide analogues is altered from the L-lysine residue found in the native protein to any other amino acid. Pharmaceutical compositions of the peptide analogues are provided. In addition, the peptide analogues are administered to patients with multiple sclerosis.