The present invention provides a multiple-wheel input device comprising a positioning plate, two light-penetrating type encode wheels, a circuit board, and two hollow rollers. The light-penetrating type encode wheel is connected pivotally to both sides of the positioning plate. A gap hole is disposed at the central part of the bottom edge of the positioning plate. Two inclined surfaces are formed at the top edge of the gap hole. An arched board is installed at each side of the gap hole. A fixing bar is installed adjoining to each side of the bottom edge of the gap hole to join the circuit board. A light-emitting device is installed at the central part of the circuit board. A light-receiving device is installed at each side of the light-emitting device. The hollow roller is connected pivotally to the circumference of one side of each encode wheel and outside the two arched boards. When the roller is turned, the encode wheel is jointly turned synchronously. The light emitted from the light-emitting device is reflected by the inclined surface, penetrates the transparent portion of the encode wheel, and is received by the corresponding light-receiving device. The light variation signals are converted to the current variation signals of the light-receiving device. The movements in the X-Y coordinates of the input device (mouse) can thus be known according to the output signals of the encode wheel.