发明授权
US06495514B1 Method for reducing inflammation and inducing an analgesic effect and compounds thereof 失效
降低炎症并诱导止痛效果的方法及其化合物

  • 专利标题: Method for reducing inflammation and inducing an analgesic effect and compounds thereof
  • 专利标题(中): 降低炎症并诱导止痛效果的方法及其化合物
  • 申请号: US09010162
    申请日: 1998-01-21
  • 公开(公告)号: US06495514B1
    公开(公告)日: 2002-12-17
  • 发明人: Sheldon W. MayStanley H. Pollock
  • 申请人: Sheldon W. MayStanley H. Pollock
  • 主分类号: A61K3800
  • IPC分类号: A61K3800
Method for reducing inflammation and inducing an analgesic effect and compounds thereof
摘要:
The invention relates to a method for reducing inflammation in a subject by administering to the subject an effective amount of the compound having the structure I or II: wherein, R1 is C1-C10 branched or straight chain alkyl, aryl, an amino acid, or a peptide; and R2 is hydrogen or lower C1-C5 branched or straight alkyl, or the salt or ester thereof, wherein the stereochemistry about the carbon-carbon double bond is trans. The invention further relates to a method of inducing an analgesic effect by administering to a subject an effective amount of the compound having the structure I or II. The invention further relates to a compound having the structure II, wherein, R1 is an N-acyl amino acid or peptide, or the salt or ester thereof.
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