发明授权
- 专利标题: Thienopyrimidine-based inhibitors of the Src family
- 专利标题(中): 基于噻吩并嘧啶的Src家族抑制剂
-
申请号: US09694145申请日: 2000-10-23
-
公开(公告)号: US06503914B1公开(公告)日: 2003-01-07
- 发明人: Michele A. Benish , Michael Lawless , Raymond J. A. Budde
- 申请人: Michele A. Benish , Michael Lawless , Raymond J. A. Budde
- 主分类号: C07D49504
- IPC分类号: C07D49504
摘要:
Various thienopyrimidine-based analog compounds that selectively inhibit the Src family of tyrosine kinases. These compounds are thienopyrimidines and contain a hydrozone bridge created by heating a thienopyrimidine hydrazine with an aldehyde in ethanol at reflux. Such compounds are useful in the treatment of various diseases including hyperproliferative diseases, hematologic diseases, osteoporosis, neurological diseases, autoimmune diseases, allergic/immunological diseases, or viral infections.