发明授权
- 专利标题： D-proline derivatives
- 专利标题（中）： D-脯氨酸衍生物
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申请号： US09636076申请日： 2000-08-10
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公开(公告)号： US06512001B1公开(公告)日： 2003-01-28
- 发明人: Cornelia Hertel , Torsten Hoffmann , Roland Jakob-Roetne , Roger David Norcross
- 申请人： Cornelia Hertel , Torsten Hoffmann , Roland Jakob-Roetne , Roger David Norcross
- 优先权： EP97119031 19971031; EP98113851 19980724
- 主分类号： A61K314025
- IPC分类号： A61K314025
摘要：
New compounds have the formula: wherein R, R1, X and Y have the meanings described herein. Methods are set forth for synthesizing these compounds and using these compounds to treat diseases associated with amyloidosis, such as Alzheimer's disease, maturity onset diabetes mellitus, familial amyloid polyneuropathy, scrapie, and Kreuzfeld-Jacob disease.
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