发明授权
- 专利标题： Compositions and methods for intraductal gene therapy
- 专利标题（中）： 导管内基因治疗的组成和方法
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申请号： US09488464申请日： 2000-01-20
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公开(公告)号： US06514695B1公开(公告)日： 2003-02-04
- 发明人: Sanford H. Barsky , Mary L. Alpaugh
- 申请人： Sanford H. Barsky , Mary L. Alpaugh
- 主分类号： C12Q168
- IPC分类号： C12Q168
摘要：
The present invention provides methods for the selective transduction of a cell in a ductal system in a mammary gland by contacting, via ductal cannulation, the cell with a vector that selectively targets the cell. In this context, the invention provides prophylactic and therapeutic methods of treating the ductal epithelium of the breast, for disease, in particular cancer. The present invention further provides diagnostic methods of determining the presence of disease in the ductal epithelium of the breast, in particular cancer.
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