发明授权
US06531498B1 Isoxazole derivatives to be used as phosphodiesterase VII inhibitors
失效
异恶唑衍生物用作磷酸二酯酶VII抑制剂
- 专利标题: Isoxazole derivatives to be used as phosphodiesterase VII inhibitors
- 专利标题(中): 异恶唑衍生物用作磷酸二酯酶VII抑制剂
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申请号: US10129270申请日: 2002-05-03
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公开(公告)号: US06531498B1公开(公告)日: 2003-03-11
- 发明人: Hans-Michael Eggenweiler , Rochus Jonas , Michael Wolf , Michael Gassen , Thomas Welge
- 申请人: Hans-Michael Eggenweiler , Rochus Jonas , Michael Wolf , Michael Gassen , Thomas Welge
- 优先权: DE19953024 19991104
- 主分类号: C07D26106
- IPC分类号: C07D26106
摘要:
The invention relates to compounds of formula I and to their physiologically acceptable salts and solvates which act as phosphodiesterse VII inhibitors and are thus useful for the treatment of allergic disorders, asthma, chronic bronchitis, atopic dermatitis, psoriasis and other skin disorders, inflammatory disorders, autoimmune diseases, rheumatoid arthritis, multiple sclerosis, Crohn's disease, diabetes mellitus or ulcerative colitis, osteoporosis, transplant rejection reactions, cachexia, tumor growth, tumor metastases, sepsis, memory disturbances, atherosclerosis and AIDS.
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