发明授权
US06531498B1 Isoxazole derivatives to be used as phosphodiesterase VII inhibitors 失效
异恶唑衍生物用作磷酸二酯酶VII抑制剂

Isoxazole derivatives to be used as phosphodiesterase VII inhibitors
摘要:
The invention relates to compounds of formula I and to their physiologically acceptable salts and solvates which act as phosphodiesterse VII inhibitors and are thus useful for the treatment of allergic disorders, asthma, chronic bronchitis, atopic dermatitis, psoriasis and other skin disorders, inflammatory disorders, autoimmune diseases, rheumatoid arthritis, multiple sclerosis, Crohn's disease, diabetes mellitus or ulcerative colitis, osteoporosis, transplant rejection reactions, cachexia, tumor growth, tumor metastases, sepsis, memory disturbances, atherosclerosis and AIDS.
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