发明授权
- 专利标题： Cyclic azapeptides with angiogenic effect
- 专利标题（中）： 具有血管生成作用的环状氮杂肽
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申请号： US09446974申请日： 2000-03-23
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公开(公告)号： US06534478B1公开(公告)日： 2003-03-18
- 发明人: Alfred Jonczyk , Simon Goodman , Horst Kessler , Jochen Wermuth , Jörg Schmitt
- 申请人： Alfred Jonczyk , Simon Goodman , Horst Kessler , Jochen Wermuth , Jörg Schmitt
- 优先权： DE19728524 19970704
- 主分类号： A61K3800
- IPC分类号： A61K3800
摘要：
Compounds of the formula I cyclo-(aArg-aGly-aAsp-aX-aY) I in which aArg, aGly, aAsp, aX and aY have the meanings indicated in claim 1, and their salts, can be used as integrin inhibitors, in particular for the prophylaxis and treatment of diseases of the circulation, in thrombosis, cardiac infarct, coronary heart diseases, arteriosclerosis, in pathological processes which are supported or propagated by angiogenesis and in tumour therapy.
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