- 专利标题: Inhibitors of prenyl-protein transferase
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申请号: US09828259申请日: 2001-04-06
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公开(公告)号: US06534506B2公开(公告)日: 2003-03-18
- 发明人: Diem N. Nguyen , Craig A. Stump , Theresa M. Williams
- 申请人: Diem N. Nguyen , Craig A. Stump , Theresa M. Williams
- 主分类号: C07D49822
- IPC分类号: C07D49822
摘要:
The present invention is directed to peptidomimetic macrocyclic compounds which inhibit prenyl-protein transferase and the prenylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting prenyl-protein transferase and the prenylation of the oncogene protein Ras.
公开/授权文献
- US20020123497A1 Inhibitors of prenyl-protein transferase 公开/授权日:2002-09-05
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