A self-driven centrifuge for separating particulate matter out of a circulating liquid includes a base having a pair of tangential jet nozzles for generating the self-driven force. Connected to the base is a centrifuge shell which defines a hollow interior space. A disposable liner is positioned within the centrifuge shell. A hollow rotor hub is assembled to the base and extends through the hollow interior space. A support plate is positioned within the hollow interior space and, in cooperation with the rotor hub, defines an annular flow exit. Positioned within the hollow interior space is a unitary separation vane module which is constructed and arranged so as to extend around the rotor hub. The separation vane module includes a plurality of axially-extending and spaced-apart separation vanes. In one embodiment the vane module and a liner shell are formed as a unitary component.