发明授权
US06545005B1 Mediators of hedgehog signaling pathways, compositions and uses related thereto
有权
刺猬信号通路的调解者，与之相关的组合物和用途
- 专利标题： Mediators of hedgehog signaling pathways, compositions and uses related thereto
- 专利标题（中）： 刺猬信号通路的调解者，与之相关的组合物和用途
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申请号： US09663835申请日： 2000-09-15
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公开(公告)号： US06545005B1公开(公告)日： 2003-04-08
- 发明人: Anthony David Baxter , Edward Andrew Boyd , Oivin M. Guicherit , Stephen Price , Lee D. Rubin
- 申请人： Anthony David Baxter , Edward Andrew Boyd , Oivin M. Guicherit , Stephen Price , Lee D. Rubin
- 主分类号： A61K31505
- IPC分类号： A61K31505
摘要：
The present invention makes available methods and reagents for inhibiting aberrant growth states resulting from hedgehog gain-of-function by contacting the cell with a hedgehog antagonist, such as a small molecule, in a sufficient amount to aberrant growth state, e.g., to agonize a normal ptc pathway or antagonize hedgehog activity.
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