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发明授权
US06548061B1 Immunological composition and its method of use to transiently disrupt mammalian central nervous system myelin to promote neuronal regeneration 失效
免疫组成及其使用方法瞬时破坏哺乳动物中枢神经系统髓鞘以促进神经元再生

  • 专利标题： Immunological composition and its method of use to transiently disrupt mammalian central nervous system myelin to promote neuronal regeneration
  • 专利标题（中）： 免疫组成及其使用方法瞬时破坏哺乳动物中枢神经系统髓鞘以促进神经元再生
  • 申请号： US09181719
    申请日： 1998-10-28
  • 公开(公告)号： US06548061B1
    公开(公告)日： 2003-04-15
  • 发明人: John D. Steeves , Jason K. Dyer , Hans S. Keirstead
  • 申请人： John D. Steeves , Jason K. Dyer , Hans S. Keirstead
  • 优先权： CA2219683 19971028; CA2251410 19981016
  • 主分类号： A61K39395
  • IPC分类号： A61K39395
Immunological composition and its method of use to transiently disrupt mammalian central nervous system myelin to promote neuronal regeneration
摘要：
Novel compositions are described comprising the combined administration of serum complement proteins with complement-fixing antibodies. The antibodies specifically bind to one or more epitopes of myelin, and complement proteins. These compositions are useful for promoting regrowth, repair, and regeneration of neurons in the CNS of a mammalian subject. The compositions and method can be used following immediate or chronic injury.
摘要（中）：

描述新的组合物，其包括将血清补体蛋白与补体定影抗体联合施用。 抗体特异性结合髓鞘和补体蛋白的一个或多个表位。 这些组合物可用于促进哺乳动物受试者的CNS中神经元的再生长，修复和再生。 组合物和方法可以在立即或慢性损伤后使用。

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