发明授权
US06552013B1 Deoxyamino acid compounds, pharmaceutical compositions comprising same, and methods for inhibiting &bgr;-amyloid peptide release and/or its synthesis by use of such compounds
失效
脱氧氨基酸化合物,包含其的药物组合物和通过使用这些化合物抑制β-淀粉样蛋白肽释放和/或其合成的方法
- 专利标题: Deoxyamino acid compounds, pharmaceutical compositions comprising same, and methods for inhibiting &bgr;-amyloid peptide release and/or its synthesis by use of such compounds
- 专利标题(中): 脱氧氨基酸化合物,包含其的药物组合物和通过使用这些化合物抑制β-淀粉样蛋白肽释放和/或其合成的方法
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申请号: US09338121申请日: 1999-06-22
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公开(公告)号: US06552013B1公开(公告)日: 2003-04-22
- 发明人: James E. Audia , Warren J. Porter , Richard C. Thompson , Stephen C. Wilkie , Douglas R. Stack , Qing Shi
- 申请人: James E. Audia , Warren J. Porter , Richard C. Thompson , Stephen C. Wilkie , Douglas R. Stack , Qing Shi
- 主分类号: C07D24324
- IPC分类号: C07D24324
摘要:
Disclosed are compounds which inhibit &bgr;-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits &bgr;-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.