发明授权
US06562994B2 Process for the preparation of N-(substituted phenyl)-3-alkyl-,aryl- and heteroarylsulfonyl-2-hydroxy-2-alkyl- and haloalkylpropanamide compounds
失效
制备N-（取代的苯基）-3-烷基 - ，芳基 - 和杂芳基磺酰基-2-羟基-2-烷基 - 和卤代烷基丙酰胺化合物的方法
- 专利标题： Process for the preparation of N-(substituted phenyl)-3-alkyl-,aryl- and heteroarylsulfonyl-2-hydroxy-2-alkyl- and haloalkylpropanamide compounds
- 专利标题（中）： 制备N-（取代的苯基）-3-烷基 - ，芳基 - 和杂芳基磺酰基-2-羟基-2-烷基 - 和卤代烷基丙酰胺化合物的方法
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申请号： US09953759申请日： 2001-09-17
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公开(公告)号： US06562994B2公开(公告)日： 2003-05-13
- 发明人: Bang-Chi Chen , Joseph E. Sundeen , Rulin Zhao
- 申请人： Bang-Chi Chen , Joseph E. Sundeen , Rulin Zhao
- 主分类号： C07C25500
- IPC分类号： C07C25500
摘要：
The present invention provides an improved process for the preparation of N-(substituted phenyl)-3-alkyl-, aryl- and heteroarylsulfonyl-2-hydroxy-2-alkyl- and haloalkylpropanamide compounds of formula I that exhibit antiandrogenic activity and are useful in the treatment of malignant or benign prostatic disease or of androgen dependent disease conditions such as acne, hirsutism or seborrhea.
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