发明授权
- 专利标题： Cadherin-like asymmetry protein-1, and methods for its use
- 专利标题（中）： 钙粘蛋白样不对称蛋白-1及其使用方法
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申请号： US09546934申请日： 2000-04-11
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公开(公告)号： US06565848B1公开(公告)日： 2003-05-20
- 发明人: Peter S. Lu , Mark M. Davis
- 申请人： Peter S. Lu , Mark M. Davis
- 主分类号： A61K39395
- IPC分类号： A61K39395
摘要：
The present invention relates to molecules involved in cell-cell interactions in the immune system. In particular, the invention relates to a cell surface protein which contains certain classical cadherin characteristics, but it exhibits an apical distribution pattern on the surface of lymphocytes. The membrane location of this molecule correlates with the contact interface between T and B cells, and antibodies against an extracellular domain of this protein disrupt T cell/B cell interactions.
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