发明授权
US06565869B1 Use of CNTF (ciliary neurotrophic factor) receptor activators for the treatment of obesity
有权
使用CNTF（睫状神经营养因子）受体激活剂治疗肥胖
- 专利标题： Use of CNTF (ciliary neurotrophic factor) receptor activators for the treatment of obesity
- 专利标题（中）： 使用CNTF（睫状神经营养因子）受体激活剂治疗肥胖
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申请号： US09308368申请日： 1999-07-19
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公开(公告)号： US06565869B1公开(公告)日： 2003-05-20
- 发明人: Gennaro Ciliberto , Patrizia Costa , Giacomo Paonessa , Domenico Lazzaro , Isabelle Gloaguen , Annalise Di Marco , Anna De Martis , Ralph Laufer , Riccardo Cortese
- 申请人： Gennaro Ciliberto , Patrizia Costa , Giacomo Paonessa , Domenico Lazzaro , Isabelle Gloaguen , Annalise Di Marco , Anna De Martis , Ralph Laufer , Riccardo Cortese
- 优先权： ITRM96A0790 19961119
- 主分类号： A61F202
- IPC分类号： A61F202
摘要：
The present invention refers to the use of hCNTF (human ciliary neurotrophic factor), mutants thereof or other molecules that activate the CNTF receptor, for the preparation of drugs for the treatment of obesity and associated disease, for example hyperglycemia. FIG. 1 shows the anti-obesity effect of hCNTF and leptin on body weight (left panels) and on food intake (right panels) in genetically obese mice and in mice with diet-induced obesity (DIO).
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