Solid delivery systems for controlled release of molecules incorporated therein and methods of making same

Invention Grant

US06586006B2 Solid delivery systems for controlled release of molecules incorporated therein and methods of making same 失效

Title translation: 用于控制释放分子内的固体递送系统及其制备方法

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Patent Title: Solid delivery systems for controlled release of molecules incorporated therein and methods of making same
Patent Title (中): 用于控制释放分子内的固体递送系统及其制备方法
Application No.: US09755737

Application Date: 2001-01-05
Publication No.: US06586006B2

Publication Date: 2003-07-01
Inventor: Bruce J. Roser , Camilo Colaco , Mohammed A. Z. Jerrow , Julian Blair , Jaap Kampinga , James Lewis Wardell , John Alistair Duffy
Applicant: Bruce J. Roser , Camilo Colaco , Mohammed A. Z. Jerrow , Julian Blair , Jaap Kampinga , James Lewis Wardell , John Alistair Duffy
Priority: GB9415810 19940804
Main IPC: A61K914
IPC: A61K914

Solid delivery systems for controlled release of molecules incorporated therein and methods of making same

Abstract:

The present invention encompasses solid dose delivery systems for administration of guest substances. Preferred delivery systems are suitable for delivery of bioactive materials to subcutaneous and intradermal, intramuscular, intravenous tissue, the delivery system being sized and shaped for penetrating the epidermis. The delivery systems comprises a vitreous vehicle loaded with the guest substance and capable of releasing the guest substance in situ at various controlled rates. The present invention further includes methods of making and using the solid dose delivery systems.

Abstract(Chinese):

本发明包括用于施用客体物质的固体剂量递送系统。优选的递送系统适于将生物活性物质递送到皮下和皮内，肌内，静脉内组织，所述递送系统的尺寸和形状适于穿透表皮。输送系统包括装载客体物质的玻璃体，并且能够以各种控制的速率原位释放客体物质。本发明还包括制备和使用固体剂量递送系统的方法。

Public/Granted literature

US20010038858A1 Solid delivery systems for controlled release of molecules incorporated therein and methods of making same Public/Granted day:2001-11-08

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