发明授权
US06586422B2 Pyrazine and triazine derivatives of 1,2,4,5-tetrahydro-Benzo or Thieno [d] azepine
失效
1,2,4,5-四氢 - 苯并或噻吩并[d]吖庚因的吡嗪和三嗪衍生物
![Pyrazine and triazine derivatives of 1,2,4,5-tetrahydro-Benzo or Thieno [d] azepine](/docs/US/2003-07-01/US06586422B2/abs.jpg.600x600.jpg)
- 专利标题： Pyrazine and triazine derivatives of 1,2,4,5-tetrahydro-Benzo or Thieno [d] azepine
- 专利标题（中）： 1,2,4,5-四氢 - 苯并或噻吩并[d]吖庚因的吡嗪和三嗪衍生物
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申请号： US10020680申请日： 2001-12-12
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公开(公告)号： US06586422B2公开(公告)日： 2003-07-01
- 发明人: Alfred Binggeli , Hans-Peter Maerki , Vincent Mutel , Maurice Wilhelm , Wolfgang Wostl
- 申请人： Alfred Binggeli , Hans-Peter Maerki , Vincent Mutel , Maurice Wilhelm , Wolfgang Wostl
- 优先权： EP00128329 20001222
- 主分类号： A61K3155
- IPC分类号： A61K3155
![Pyrazine and triazine derivatives of 1,2,4,5-tetrahydro-Benzo or Thieno [d] azepine](/abs-image/US/2003/07/01/US06586422B2/abs.jpg.150x150.jpg)
摘要：
The invention relates to compounds which are represented by the formula wherein R1, R2, R3, R4, X and Y are as defined in the specification, as well as pharmaceutically acceptable salts thereof. The invention further relates to pharmaceutical compositions containing these compounds and to a process for their preparation. The compounds possess affinity towards metabotropic glutamate receptors and are therefore useful in the treatment or prevention of acute and/or chronic neurological disorders.
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