发明授权
- 专利标题: &agr;, &agr;-dibromo-&agr;-chloro-acetophenones as synthons
- 专利标题(中): α,α-二溴-α-氯 - 苯乙酮作为合成子
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申请号: US10140638申请日: 2002-05-08
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公开(公告)号: US06586598B2公开(公告)日: 2003-07-01
- 发明人: Anup K. Ray , Hiren Patel , Shilpa V. Merai , Mahendra R. Patel
- 申请人: Anup K. Ray , Hiren Patel , Shilpa V. Merai , Mahendra R. Patel
- 主分类号: C07D21132
- IPC分类号: C07D21132
摘要:
This disclosure relates to the use of &agr;,&agr;-dibromo-&agr;-chloroacetophenone compounds as intermediates for the preparation of aromatic carbonyl compounds, especially aromatic amides. The compound 2,5-bis(2,2,2-trifluoroethoxy)-&agr;,&agr;-dibromo-&agr;-chloroacetophenone is especially useful as an intermediate for the preparation of flecainide, a known pharmaceutical.
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