发明授权
US06586598B2 &agr;, &agr;-dibromo-&agr;-chloro-acetophenones as synthons 有权
α,α-二溴-α-氯 - 苯乙酮作为合成子

&agr;, &agr;-dibromo-&agr;-chloro-acetophenones as synthons
摘要:
This disclosure relates to the use of &agr;,&agr;-dibromo-&agr;-chloroacetophenone compounds as intermediates for the preparation of aromatic carbonyl compounds, especially aromatic amides. The compound 2,5-bis(2,2,2-trifluoroethoxy)-&agr;,&agr;-dibromo-&agr;-chloroacetophenone is especially useful as an intermediate for the preparation of flecainide, a known pharmaceutical.
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