Substituted 10,11-benzo[b]fluoren-10-ones as estrogenic agents

Invention Grant

US06589980B2 Substituted 10,11-benzo[b]fluoren-10-ones as estrogenic agents 失效

Title translation: 取代的10,11-苯并[b]芴-10-酮作为雌激素

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Patent Title: Substituted 10,11-benzo[b]fluoren-10-ones as estrogenic agents
Patent Title (中): 取代的10,11-苯并[b]芴-10-酮作为雌激素
Application No.: US10146562

Application Date: 2002-05-15
Publication No.: US06589980B2

Publication Date: 2003-07-08
Inventor: Christopher P. Miller , Michael D. Collini , Heather A. Harris , James C. Keith, Jr.
Applicant: Christopher P. Miller , Michael D. Collini , Heather A. Harris , James C. Keith, Jr.
Main IPC: A61K3135
IPC: A61K3135

Substituted 10,11-benzo[b]fluoren-10-ones as estrogenic agents

Abstract:

This invention provides estrogen receptor modulators of formula I, having the structure wherein X, Y1, Y2, Y3, Y4, Z1, Z2, Z3, and Z4 are as defined in the specification, or a pharmaceutically acceptable salt thereof.

Abstract(Chinese):

本发明提供式I的雌激素受体调节剂，其具有其中X，Y 1，Y 2，Y 3，Y 4，Z 1，Z 2，Z 3和Z 4如本说明书中所定义的结构或其药学上可接受的盐。

Public/Granted literature

US20030087955A1 Substituted 10,11-benzo[b]fluoren-10-ones as estrogenic agents Public/Granted day:2003-05-08

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