A filter cartridge (16), especially for installation in an air filter of an internal combustion engine having a housing (10) with an inlet (12) for untreated air and an outlet (13) for clean air, the filter cartridge preferably being made of a pleated filter medium, and being provided with sealing elements on end plates (18, 19) arranged at the axial end faces of the filter cartridge. A support body (17) is provided on the inner wall of the filter cartridge with support surfaces (23) for axially and radially positioning the filter cartridge. A seal element (26) extending axially along the support body is also provided in the area of the support body.