A medicine feeder apparatus comprising a plurality of cassettes each of which contains a different kind of medicine and a base portion on which the plurality of cassettes are mounted and which discharges the medicine in accordance with the prescription. the apparatus comprises an identification which is provided on each cassette, the identification showing information on the medicine contained in the cassette; a reader which is provided on the base portion, the reader reading the identification of the cassette during the cassette is mounted on the base portion; and a rock which is provided on the base portion, the rock preventing the cassette from being mounted. If the information of the medicine read from the identification by the reader does not coincide with a previously stored information, the rock is operated, while if coincide, the rock is released.