发明授权
- 专利标题： Method for determining susceptibility to rheumatoid arthritis
- 专利标题（中）： 确定类风湿关节炎易感性的方法
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申请号： US09423861申请日： 2000-01-31
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公开(公告)号： US06623924B1公开(公告)日： 2003-09-23
- 发明人: Shunichi Shiozawa
- 申请人： Shunichi Shiozawa
- 优先权： JP9-125899 19970515; JP10-031840 19980213
- 主分类号： C12Q168
- IPC分类号： C12Q168
摘要：
The application provides genes causative of rheumatoid arthritis, which are located within ±1 centimorgan from DNA sequences to which the microsatellite markers D1S214, D1S253, D8S556, DXS1001, DXS1047, DXS1205, DXS1227 and/or DXS1232 are hybridized: a method for diagnosing rheumatoid arthritis, including amplifying the genomic DNA of a subject by PCR using at least one of the microsatellite markers as primer and comparing the PCR products thereof with the PCR products prepared in the same manner using the genomic DNA of a normal control; and a method for identifying the causative factors of rheumatoid arthritis including the same as described above.
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