发明授权
- 专利标题: Dual manifold system and method for fluid transfer
- 专利标题(中): 双歧管系统和流体传输方法
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申请号: US09262455申请日: 1999-03-04
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公开(公告)号: US06627157B1公开(公告)日: 2003-09-30
- 发明人: Mitchel J. Doktycz , William Louis Bryan , Reid Kress
- 申请人: Mitchel J. Doktycz , William Louis Bryan , Reid Kress
- 主分类号: B01L302
- IPC分类号: B01L302
摘要:
A dual-manifold assembly is provided for the rapid, parallel transfer of liquid reagents from a microtiter plate to a solid state microelectronic device having biological sensors integrated thereon. The assembly includes aspiration and dispense manifolds connected by a plurality of conduits. In operation, the aspiration manifold is actuated such that the aspiration manifold is seated onto an array of reagent-filled wells of the microtiter plate. The wells are pressurized to force reagent through conduits toward the dispense manifold. A pressure pulse provided by a standard ink-jet printhead ejects nanoliter-to-picoliter droplets of reagent through an array of printhead orifices and onto test sites on the surface of the microelectronic device.