发明授权
US06630155B1 Controlled release liquid delivery compositions with low initial drug burst
有权
具有低初始药物爆发的控制释放液体递送组合物
- 专利标题: Controlled release liquid delivery compositions with low initial drug burst
- 专利标题(中): 具有低初始药物爆发的控制释放液体递送组合物
-
申请号: US09643289申请日: 2000-08-22
-
公开(公告)号: US06630155B1公开(公告)日: 2003-10-07
- 发明人: Bhagya L. Chandrashekar , Mingxing Zhou , Eileen M. Jarr , Richard L. Dunn
- 申请人: Bhagya L. Chandrashekar , Mingxing Zhou , Eileen M. Jarr , Richard L. Dunn
- 主分类号: A61F200
- IPC分类号: A61F200
摘要:
The invention provides a controlled release polymeric composition which includes a base polymer or copolymer, an organic solvent, a polymeric controlled release additive, and a biologically active agent. The polymeric controlled release additive reduces the initial burst of biologically active agent released from the polymeric composition as it is solidifying to form the solid implant. The controlled release additive is preferably a poly(lactide-co-glycolide)/polyethylene glycol block copolymer.
信息查询