发明授权
US06630155B1 Controlled release liquid delivery compositions with low initial drug burst 有权
具有低初始药物爆发的控制释放液体递送组合物

Controlled release liquid delivery compositions with low initial drug burst
摘要:
The invention provides a controlled release polymeric composition which includes a base polymer or copolymer, an organic solvent, a polymeric controlled release additive, and a biologically active agent. The polymeric controlled release additive reduces the initial burst of biologically active agent released from the polymeric composition as it is solidifying to form the solid implant. The controlled release additive is preferably a poly(lactide-co-glycolide)/polyethylene glycol block copolymer.
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