发明授权
US06630457B1 Functionalized derivatives of hyaluronic acid, formation of hydrogels in situ using same, and methods for making and using same
失效
透明质酸的官能化衍生物，使用它们原位形成水凝胶，以及制备和使用它们的方法
- 专利标题： Functionalized derivatives of hyaluronic acid, formation of hydrogels in situ using same, and methods for making and using same
- 专利标题（中）： 透明质酸的官能化衍生物，使用它们原位形成水凝胶，以及制备和使用它们的方法
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申请号： US09156829申请日： 1998-09-18
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公开(公告)号： US06630457B1公开(公告)日： 2003-10-07
- 发明人: Daniel Aeschlimann , Paul Bulpitt
- 申请人： Daniel Aeschlimann , Paul Bulpitt
- 主分类号： A61K3800
- IPC分类号： A61K3800
摘要：
Methods for chemical modification of hyaluronic acid, formation of amine or aldehyde functionalized hyaluronic acid, and the cross-linking thereof to form hydrogels are provided. Functionalized hyaluronic acid hydrogels of this invention can be polymerized in situ, are biodegradable, and can serve as a tissue adhesive, a tissue separator, a drug delivery system, a matrix for cell cultures, and a temporary scaffold for tissue regeneration.
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