发明授权
US06635421B1 Neuropilins and use thereof in methods for diagnosis and prognosis of cancer
有权
神经胶质蛋白及其在癌症诊断和预后方法中的应用
- 专利标题： Neuropilins and use thereof in methods for diagnosis and prognosis of cancer
- 专利标题（中）： 神经胶质蛋白及其在癌症诊断和预后方法中的应用
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申请号： US09583638申请日： 2000-05-30
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公开(公告)号： US06635421B1公开(公告)日： 2003-10-21
- 发明人: Michael Klagsbrun , Shay Soker , Hua-Quan Miao , Seiji Takashima
- 申请人： Michael Klagsbrun , Shay Soker , Hua-Quan Miao , Seiji Takashima
- 主分类号： C12Q168
- IPC分类号： C12Q168
摘要：
The present invention relates to VEGF receptors (VEGFR) and neuropilins such as VEGF165R/NP-1 and NP-2 that are associated with metastatic potential of a malignant cell and their use in the diagnosis and prognosis of cancer. Preferred ones are VEGF165R/NP-1 and NP-2 but any neuropilin or VEGFR, where the constituents share at least about 85% homology with either of the above VEGF165R/NP-1 and NP-2 can be used. More preferably, such constituent shares at least 90% homology. Still more preferably, each constituent shares at least 95% homology.