发明授权
- 专利标题： N-(4-carbamimidoyl-phenyl)-glycine derivatives
- 专利标题（中）： N-（4-甲脒基 - 苯基） - 甘氨酸衍生物
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申请号： US10350617申请日： 2003-01-24
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公开(公告)号： US06642386B2公开(公告)日： 2003-11-04
- 发明人: Leo Alig , Katrin Groebke Zbinden , Ulrike Obst
- 申请人： Leo Alig , Katrin Groebke Zbinden , Ulrike Obst
- 优先权： EP02002009 20020206
- 主分类号： C07D21140
- IPC分类号： C07D21140
摘要：
The invention is concerned with water soluble N-(4-carbamimidoyl-phenyl)-glycine derivatives of formula (I) wherein R1 to R4 and n are as defined in the description and in the claims, as well as physiologically acceptable salts thereof. These compounds inhibit the formation of coagulation factors Xa, IXa and thrombin induced by factor VIIa and tissue factor and can be used as medicaments.
公开/授权文献
- US20030166683A1 N-(4-CARBAMIMIDOYL-PHENYL)-GLYCINE DERIVATIVES 公开/授权日：2003-09-04
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