The present invention describes a device for intracorporal, minimal-invasive treatment of a patient, comprising a working instrument that can be introduced into a body cavity of the patient for carrying out a treatment step, wherein a distal end of the introduced working instrument defines an intracorporal working area, and at least one image pick-up unit for picking up an image of the intracorporal working area, further comprising positioning means for orienting an optical axis of the image pick-up unit in dependency on a spatial position of the intracorporal working area, wherein the positioning means comprise a guide shaft, in which the working instrument is guided, and wherein the image pick-up unit is pivotably fixed at an intracorporal portion of the guide shaft. The positioning means have a holder pivotably fixed to the intracorporal portion of the guide shaft, the image pick-up unit being arranged at the holder in a distance from a location where the holder is linked to the guide shaft, such that the image pick-up unit is intracorporally pivotable into a working position, in which the optical axis runs angularly to a longitudinal center axis of the guide shaft and points to the longitudinal center axis.