发明授权
- 专利标题: Aromatic nitrogen-containing 6-membered cyclic compounds
- 专利标题(中): 芳香族含氮6元环状化合物
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申请号: US09925892申请日: 2001-08-10
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公开(公告)号: US06656935B2公开(公告)日: 2003-12-02
- 发明人: Koichiro Yamada , Kenji Matsuki , Kenji Omori , Kohei Kikkawa
- 申请人: Koichiro Yamada , Kenji Matsuki , Kenji Omori , Kohei Kikkawa
- 优先权: JP11-261852 19990916; JP2000-130371 20000428
- 主分类号: C07D23948
- IPC分类号: C07D23948
摘要:
An aromatic nitrogen-containing 6-membered cyclic compound of the formula (I): wherein Ring A is a substituted or unsubstituted nitrogen-containing heterocyclic group; R1 is a substituted or unsubstituted lower alkyl group, —NH—Q—R3 (R3 is a substituted or unsubstituted nitrogen containing heterocyclic group, and Q is a lower alkylene group or a single bond), or —NH—R4 (R4 is a substituted or unsubstituted cycloalkyl group); R2 is a substituted or unsubstituted aryl group; one of Y and Z is ═CH—, and the other is ═N—, or a pharmaceutically acceptable salt thereof, these compounds exhibiting excellent selective PDE V inhibitory activities, and hence, being useful in the prophylaxis or treatment of penile erectile dysfunction, etc.
公开/授权文献
- US20030032647A1 Aromatic nitrogen-containing 6-membered cyclic compounds 公开/授权日:2003-02-13
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