A device and method configured for placement into the catheter access port to prevent insertion of a needle into the catheter access port. The device a prong to engage the housing and lock itself in the catheter access port, an annular surface having geometry complimentary to the catheter access port to seal the denial device, and a face configured to deny needle access to the catheter access port. The device is also self sealing to substantial prevent deposition between itself and the catheter access port, is configured to be inserted without the need for tools, and is manufactured from biocompatible material. The method for inserting this device consists of aligning the device with the catheter access port, inserting the device, confirming it is in place, and sealing it into the catheter access port.