发明授权
- 专利标题: Method of inhibiting stenosis and restenosis
- 专利标题(中): 抑制狭窄和再狭窄的方法
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申请号: US09809739申请日: 2001-03-15
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公开(公告)号: US06663863B2公开(公告)日: 2003-12-16
- 发明人: Christopher J. Horvath , Patricia E. Rao
- 申请人: Christopher J. Horvath , Patricia E. Rao
- 主分类号: A61K39395
- IPC分类号: A61K39395
摘要:
The invention relates to a method of inhibiting stenosis or restenosis in a subject. In one embodiment, an agent which inhibits recruitment and/or adhesion of neutrophils and mononuclear cells to a site of vascular injury is administered to a subject in need thereof. In another embodiment, a first agent which inhibits recruitment and/or adhesion of neutrophils to a site of vascular injury, and a second agent which inhibits recruitment and/or adhesion of mononuclear cells to a site of vascular injury are administered to a subject in need thereof. In particular embodiments, the agents are antibodies or antigen-binding fragments thereof which bind to CD18 or CCR2.
公开/授权文献
- US20020106369A1 Method of inhibiting stenosis and restenosis 公开/授权日:2002-08-08