发明授权
- 专利标题： Solid phase nitrile synthesis
- 专利标题（中）： 固相腈合成
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申请号： US10031221申请日： 2002-08-13
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公开(公告)号： US06664410B1公开(公告)日： 2003-12-16
- 发明人: Ryszard Kobylecki , Neal David Hone , Lloyd James Payne
- 申请人： Ryszard Kobylecki , Neal David Hone , Lloyd James Payne
- 优先权： GB9916575 19990715
- 主分类号： C07C25300
- IPC分类号： C07C25300
摘要：
A nitrile compound is prepared by treating a solid supported amide to dehydrate it and cleave it from the support in one operation. The preparation involves acetylation of the amide compound in the presence of a base at a temperature of less than 100° C.
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