发明授权
- 专利标题: CD30 ligand
- 专利标题(中): CD30配体
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申请号: US09628126申请日: 2000-07-28
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公开(公告)号: US06667039B1公开(公告)日: 2003-12-23
- 发明人: Raymond G. Goodwin , Craig A. Smith , Richard J. Armitage , Hans-Juergen Gruss
- 申请人: Raymond G. Goodwin , Craig A. Smith , Richard J. Armitage , Hans-Juergen Gruss
- 主分类号: A61K39385
- IPC分类号: A61K39385
摘要:
There is disclosed a polypeptide (CD30-L) and DNA sequences, vectors and transformed host cells useful in providing CD30-L polypeptides. The CD30-L polypeptide binds to the receptor known as CD30, which is expressed on a number of cell types, among which are Hodgkin's Disease tumor cells, large cell anaplasdic lymphoma cells, adult T-cell leukemia (T-ALL) cells, and a number of other malignant cell types. CD30-L polypeptides find use as carriers for delivering diagnostic and cytotoxic agents to cells expressing the CD30 receptor.
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