发明授权
- 专利标题： Hydrophilic light absorbing indole compounds for determination of physiological function in critically ill patients
- 专利标题（中）： 亲水性光吸收吲哚化合物，用于确定重症患者的生理功能
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申请号： US09688943申请日： 2000-10-16
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公开(公告)号： US06669926B1公开(公告)日： 2003-12-30
- 发明人: Samuel Achilefu , Raghavan Rajagopalan , Richard B. Dorshow , Joseph E. Bugaj
- 申请人： Samuel Achilefu , Raghavan Rajagopalan , Richard B. Dorshow , Joseph E. Bugaj
- 主分类号： A61B1000
- IPC分类号： A61B1000
摘要：
Highly hydrophilic indole and benzoindole derivatives that absorb and fluoresce in the visible region of light are disclosed. These compounds are useful for physiological and organ function monitoring. Particularly, the molecules of the invention are useful for optical diagnosis of renal and cardiac diseases and for estimation of blood volume in vivo.
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