发明授权
US06673602B1 Herpes simplex virus amplicon vector targeting system and method of using same
失效
单纯疱疹病毒扩增子载体靶向系统及其使用方法
- 专利标题: Herpes simplex virus amplicon vector targeting system and method of using same
- 专利标题(中): 单纯疱疹病毒扩增子载体靶向系统及其使用方法
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申请号: US09592537申请日: 2000-06-12
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公开(公告)号: US06673602B1公开(公告)日: 2004-01-06
- 发明人: Matthew A. Spear , Xandra O. Breakefield
- 申请人: Matthew A. Spear , Xandra O. Breakefield
- 主分类号: C12N1500
- IPC分类号: C12N1500
摘要:
The present invention relates to herpes simplex virus (HSV) amplicon vectors, and in particular, HSV-1 amplicon vectors, which have been genetically modified and used alone or with consequent genetically modified HSV virus, to target a selected cell type, such as neoplastic cells. The present invention also relates to methods of using such vectors to target a cell, in order to treat a pathologic condition, such as cancer.
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